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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Kazan medical journal</journal-id><journal-title-group><journal-title xml:lang="en">Kazan medical journal</journal-title><trans-title-group xml:lang="ru"><trans-title>Казанский медицинский журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0368-4814</issn><issn publication-format="electronic">2587-9359</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">64535</article-id><article-id pub-id-type="doi">10.17816/kazmj64535</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Use of flutikazone proponate in the treatment of patients with grave forms of bronchial asthma</article-title><trans-title-group xml:lang="ru"><trans-title>Применение флутиказона пропионата в лечении больных с тяжелыми формами бронхиальной астмы</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Fassakhov</surname><given-names>R. S.</given-names></name><name xml:lang="ru"><surname>Фассахов</surname><given-names>Р. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Professor, Head of the Department of Allergology</p> <p> </p><p> </p> </bio><bio xml:lang="ru"><p>Профессор, заведующий кафедрой аллергологии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Salieva</surname><given-names>E. V.</given-names></name><name xml:lang="ru"><surname>Салиева</surname><given-names>Е. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Allergology</p></bio><bio xml:lang="ru"><p>Кафедра аллергологии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Kazan State Medical Academy of Postgraduate Education</institution></aff><aff><institution xml:lang="ru">Казанская государственная медицинская академия последипломного образования</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="1998-09-14" publication-format="electronic"><day>14</day><month>09</month><year>1998</year></pub-date><volume>79</volume><issue>5</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>343</fpage><lpage>345</lpage><history><date date-type="received" iso-8601-date="2021-04-02"><day>02</day><month>04</month><year>2021</year></date><date date-type="accepted" iso-8601-date="2021-04-02"><day>02</day><month>04</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 1998, Fassakhov R.S., Salieva E.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 1998, Фассахов Р.С., Салиева Е.В.</copyright-statement><copyright-year>1998</copyright-year><copyright-holder xml:lang="en">Fassakhov R.S., Salieva E.V.</copyright-holder><copyright-holder xml:lang="ru">Фассахов Р.С., Салиева Е.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://kazanmedjournal.ru/kazanmedj/article/view/64535">https://kazanmedjournal.ru/kazanmedj/article/view/64535</self-uri><abstract xml:lang="en"><p>The high efficiency of inhalation of one ofglucocorticosteroid hormones — flutikazone proponate is shown. The drug in the form of the dosed aerosol inhalator was successfully used in 24 patients with medium grave and grave course of the disease considering it as an alternative to the systemic use of glucocorticosteroids.</p></abstract><trans-abstract xml:lang="ru"><p>Бронхиальная астма является одним из наиболее распространенных и тяжелых заболеваний легких. Прогрессирующее течение с последующими частыми госпитализациями, а также высокий процент инвалидизации при астме являются, как правило, следствием запоздалой диагностики и неадекватной терапии.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Kazan Medical archive</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>Казанский медицинский архив</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Чучалин А.Г.//Тер. арх. — 1994. — № 3. — С. 3-8.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Davis D.S.// Postgrad. Med. 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