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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Kazan medical journal</journal-id><journal-title-group><journal-title xml:lang="en">Kazan medical journal</journal-title><trans-title-group xml:lang="ru"><trans-title>Казанский медицинский журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0368-4814</issn><issn publication-format="electronic">2587-9359</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">63745</article-id><article-id pub-id-type="doi">10.17816/kazmj63745</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Fundamental and applied aspects of immunohistochemical diagnosis of tumors in a person</article-title><trans-title-group xml:lang="ru"><trans-title>Фундаментальные и прикладные аспекты иммуногистохимической диагностики опухолей человека</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Petrov</surname><given-names>S. V.</given-names></name><name xml:lang="ru"><surname>Петров</surname><given-names>С. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Pathological Anatomy</p></bio><bio xml:lang="ru"><p>Отдел патологической анатомии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Balatenko</surname><given-names>N. V.</given-names></name><name xml:lang="ru"><surname>Балатенко</surname><given-names>Н. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Pathological Anatomy</p></bio><bio xml:lang="ru"><p>Отдел патологической анатомии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kozyreva</surname><given-names>N. F.</given-names></name><name xml:lang="ru"><surname>Козырева</surname><given-names>Н. Ф.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Pathological Anatomy</p></bio><bio xml:lang="ru"><p>Отдел патологической анатомии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Vinokurova</surname><given-names>G. I.</given-names></name><name xml:lang="ru"><surname>Винокурова</surname><given-names>Г. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Pathological Anatomy</p></bio><bio xml:lang="ru"><p>Отдел патологической анатомии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Mazitova</surname><given-names>F. M.</given-names></name><name xml:lang="ru"><surname>Мазитова</surname><given-names>Ф. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Pathological Anatomy</p></bio><bio xml:lang="ru"><p>Отдел патологической анатомии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Khasanov</surname><given-names>R. Sh.</given-names></name><name xml:lang="ru"><surname>Хасанов</surname><given-names>Р. Ш.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Chief Physician of the Department of Pathological Anatomy</p></bio><bio xml:lang="ru"><p>Главный врач отдела патологической анатомии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Raikhlin</surname><given-names>N. T.</given-names></name><name xml:lang="ru"><surname>Райхлин</surname><given-names>Н. Т.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Pathological Anatomy</p></bio><bio xml:lang="ru"><p>Отдел патологической анатомии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Clinical Cancer Center</institution></aff><aff><institution xml:lang="ru">Клинический онкологический центр МЗ РТ</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Research Institute of Clinical Oncology</institution></aff><aff><institution xml:lang="ru">НИИ клинической онкологии</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Cancer Research Center of the Russian Academy of Medical Sciences</institution></aff><aff><institution xml:lang="ru">Онкологический научный центр РАМН</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="1998-03-25" publication-format="electronic"><day>25</day><month>03</month><year>1998</year></pub-date><volume>79</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>114</fpage><lpage>119</lpage><history><date date-type="received" iso-8601-date="2021-03-20"><day>20</day><month>03</month><year>2021</year></date><date date-type="accepted" iso-8601-date="2021-03-20"><day>20</day><month>03</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 1998, Petrov S.V., Balatenko N.V., Kozyreva N.F., Vinokurova G.I., Mazitova F.M., Khasanov R.S., Raikhlin N.T.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 1998, Петров С.В., Балатенко Н.В., Козырева Н.Ф., Винокурова Г.И., Мазитова Ф.М., Хасанов Р.Ш., Райхлин Н.Т.</copyright-statement><copyright-year>1998</copyright-year><copyright-holder xml:lang="en">Petrov S.V., Balatenko N.V., Kozyreva N.F., Vinokurova G.I., Mazitova F.M., Khasanov R.S., Raikhlin N.T.</copyright-holder><copyright-holder xml:lang="ru">Петров С.В., Балатенко Н.В., Козырева Н.Ф., Винокурова Г.И., Мазитова Ф.М., Хасанов Р.Ш., Райхлин Н.Т.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://kazanmedjournal.ru/kazanmedj/article/view/63745">https://kazanmedjournal.ru/kazanmedj/article/view/63745</self-uri><abstract xml:lang="en"><p>The role of immunohistochemistry in the solution of a series of clinial oncology problems is studied on the basis of 300 observations taking into account current demands of histogenetic diagnosis of tumors. The most rational schemes of immunohistochemical diagnosis based on the use of minimum set of antibodies at the first and second stages of the study are given. The importance of the use of immunohistochemistry in differential histogenetic diagnosis of the most widely met tumors of a person is emphasized. This method significantly extends the possibilities of morphological verification of tumors. The prospects of the development of histochemistry for oncologic clinics are considered.</p></abstract><trans-abstract xml:lang="ru"><p>Рост частоты злокачественных новообразований и возрастающие в связи с этим требования к диагностике и лечению опухолей предполагают использование самых последних достижений в мировой науке. Одним из новых методов морфологической диагностики новообразований является иммуногистохимия (ИГХ) опухоли, основанная на иммунологических реакциях выявления в опухолевых клетках большого ряда специфических антигенов [10—12].</p></trans-abstract><kwd-group xml:lang="en"><kwd>Kazan Medical archive</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>Казанский медицинский архив</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Белоус ТА, Литвинова Л.В., Франк Г.А.//Арх. патол. — 1994. — № 1. — С. 46—50.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Гелыитейн В.И., Чипышева Т.А., Ермилова В.Д.и др.//Арх. патол. — 1990. — № 9. — С. 12—18.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Казанцева И.А., Калинин А.П., Полякова Г.А. и др.//Арх. патол. — 1995. — № 3. — С. 31—35.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Петров С.В., Райхлин Н. 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