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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Kazan medical journal</journal-id><journal-title-group><journal-title xml:lang="en">Kazan medical journal</journal-title><trans-title-group xml:lang="ru"><trans-title>Казанский медицинский журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0368-4814</issn><issn publication-format="electronic">2587-9359</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">63743</article-id><article-id pub-id-type="doi">10.17816/kazmj63743</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Metabolic processes during physiologic pregnancy in unfavourable ecologic conditions</article-title><trans-title-group xml:lang="ru"><trans-title>Состояние здоровья юных женщин и их реабилитация после родов и абортов</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Tukhvatullina</surname><given-names>L. M.</given-names></name><name xml:lang="ru"><surname>Тухватуллина</surname><given-names>Л. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Associate Professor, Head of the Department of Obstetrics and Gynecology</p></bio><bio xml:lang="ru"><p>Доцент, заведующий кафедрой акушерства и гинекологии</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Chechulina</surname><given-names>O. V.</given-names></name><name xml:lang="ru"><surname>Чечулина</surname><given-names>О. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Obstetrics and Gynecology No. 2</p></bio><bio xml:lang="ru"><p>Кафедра акушерства и гинекологии № 2</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Mansurova</surname><given-names>T. N.</given-names></name><name xml:lang="ru"><surname>Мансурова</surname><given-names>Т. Н.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Obstetrics and Gynecology No. 2</p></bio><bio xml:lang="ru"><p>Кафедра акушерства и гинекологии № 2</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Kazan State Medical Academy of Postgraduate Education</institution></aff><aff><institution xml:lang="ru">Казанская государственная медицинская академия последипломного образования</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="1998-03-25" publication-format="electronic"><day>25</day><month>03</month><year>1998</year></pub-date><volume>79</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>103</fpage><lpage>108</lpage><history><date date-type="received" iso-8601-date="2021-03-20"><day>20</day><month>03</month><year>2021</year></date><date date-type="accepted" iso-8601-date="2021-03-20"><day>20</day><month>03</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 1998, Tukhvatullina L.M., Chechulina O.V., Mansurova T.N.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 1998, Тухватуллина Л.М., Чечулина О.В., Мансурова Т.Н.</copyright-statement><copyright-year>1998</copyright-year><copyright-holder xml:lang="en">Tukhvatullina L.M., Chechulina O.V., Mansurova T.N.</copyright-holder><copyright-holder xml:lang="ru">Тухватуллина Л.М., Чечулина О.В., Мансурова Т.Н.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://kazanmedjournal.ru/kazanmedj/article/view/63743">https://kazanmedjournal.ru/kazanmedj/article/view/63743</self-uri><abstract xml:lang="en"><p>The peculiarities of metabolic and oxidation — reduction processes as well as energoplastic metabolism during physiologic course of gestation in unfavourable écologie conditions are studied. It is established that in ecologically unfavourable region during physiologic pregnancy general degydrogenase activity of blood plasma increases, cell membranes are packed, general protein level increases. The decrease of general degydrogenase activity of blood plasma with the increase of pregnancy length, rarefaction of membranes, the reduction of relation coefficient of malate dehydrogenase and lactate degydrogenase activity, the increase of combined quantity relationship of reduced and oxidated equivalents can be considered to be biomarkers of physiologic pregnancy transfer to pathologic.</p></abstract><trans-abstract xml:lang="ru"><p>Вопросы ювенильного акушерства и гинекологии изучаются практически два столетия. Первое сообщение о беременности 9-летней девочки относится к 1751 г. (Haller, Швейцария). С начала XIX века регулярно появляются сообщения о течении родов у юных женщин в возрасте от 13,5 до 19 лет.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Kazan Medical archive</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>Казанский медицинский архив</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Веселов Н.Г. и др. // Здравоохранение РСФСР. — 1986. - № 6. — С. 17-20.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Гаврилова Л.В.// Планирование семьи. — 1996. — № 4. — С. 19—24.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Гинекологическая патология детского и подроскового возраста./Под ред. З.Ш. Гилязут- диновой. — Казань, 1994.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Игнатьева Р.К., Ингамов Д.А. Медикосоциальные проблемы юного материнства. — М., 1992.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Орел В.И. 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