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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Kazan medical journal</journal-id><journal-title-group><journal-title xml:lang="en">Kazan medical journal</journal-title><trans-title-group xml:lang="ru"><trans-title>Казанский медицинский журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0368-4814</issn><issn publication-format="electronic">2587-9359</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">62456</article-id><article-id pub-id-type="doi">10.17816/kazmj62456</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Unknown</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Intensive glucocorticoid treatment</article-title><trans-title-group xml:lang="ru"><trans-title>Интенсивное лечение глюкокортикоидами</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Plotkin</surname><given-names>V. I.</given-names></name><name xml:lang="ru"><surname>Плоткин</surname><given-names>В. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff id="aff1"><institution></institution></aff><pub-date date-type="pub" iso-8601-date="1978-07-15" publication-format="electronic"><day>15</day><month>07</month><year>1978</year></pub-date><volume>59</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>58</fpage><lpage>64</lpage><history><date date-type="received" iso-8601-date="2021-03-02"><day>02</day><month>03</month><year>2021</year></date><date date-type="accepted" iso-8601-date="2021-03-02"><day>02</day><month>03</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 1978, Plotkin V.I.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 1978, Плоткин В.И.</copyright-statement><copyright-year>1978</copyright-year><copyright-holder xml:lang="en">Plotkin V.I.</copyright-holder><copyright-holder xml:lang="ru">Плоткин В.И.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://kazanmedjournal.ru/kazanmedj/article/view/62456">https://kazanmedjournal.ru/kazanmedj/article/view/62456</self-uri><abstract xml:lang="en"><p>Steroid hormones are powerful drugs the likes of which medicine has never had. EM Tareev [10], referring to the treatment of patients with systemic lupus erythematosus, wrote: “Already the first experience of hormonal therapy for systemic lupus erythematosus, even with the use of low doses and short courses, testified (as in the treatment of rheumatoid arthritis) about striking, symptomatic efficacy not previously attainable by any other treatment</p></abstract><trans-abstract xml:lang="ru"><p>Стероидные гормоны — могучие лекарственные средства, подобных которым медицина никогда не имела. Е. М. Тареев [10], касаясь вопросов лечения больных системной красной волчанкой, писал: «Уже первый опыт гормональной терапии системной красной волчанки, даже при применении невысоких доз и коротких курсов, свидетельствовал (как и при лечении ревматоидного артрита) о разительной, не достижимой ранее никаким иным лечением симптоматической ее эффективности</p></trans-abstract><kwd-group xml:lang="en"><kwd>Kazan Medical archive</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>Казанский медицинский архив</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Вогралик В. Г. Гормоны и гормональные препараты в клинике внутренних болезней. М., «Медицина», 1974</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Голиков А. Н., Бобков А. И. Тер. арх., 1974, 10</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Горизонтов П. Д., Протасова Т. Н. Роль АКТГ и кортикостероидов в патологии. 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