Kazan medical journalKazan medical journal0368-48142587-9359Eco-Vector5968210.17816/kazmj59682Research ArticleFeatures of neuro-humoral disorders in the pathology of the hypothalamusBilyalovM. Sh.info@eco-vector.com150819796049112901202129012021Copyright © 2021, Bilyalov M.S.2021<p>Neurohumoral relationships were studied in patients with primary pathology of the hypothalamus, accompanied by allergic reactions (27 people), and in those suffering from allergic diseases (bronchial asthma, Quincke's edema, drug allergy, etc.) with secondary involvement in the pathological process of the hypothalamus (35 people). Significant dysfunctions of the sympatho-adrenal, hypothalamic-pituitary-adrenal systems, serotonin-monoamine oxidase, acetylcholine-cholinesterase and heparin systems were revealed. Desensitizing and antiallergic therapy had a significant positive effect in most patients. Along with this, the content (or a tendency towards its normalization) of biologically active substances in the body fluids, reflecting the state of various adaptive systems, was normalized.</p>гипоталамусреактивностьнейро-гуморальные нарушения