Kazan medical journalKazan medical journal0368-48142587-9359Eco-Vector5962210.17816/kazmj59622Research ArticleTreatment of patients with obliterating diseases of the artery of the extremities with high doses of nicotinic acidAhrem-AhremovichR. M.info@eco-vector.comLakshinaL. K.info@eco-vector.comInstitute of Therapy, USSR Academy of Medical Sciences29111967486151728012021Copyright © 2021, Ahrem-Ahremovich R.M., Lakshina L.K.2021<p>Experimental and clinical studies carried out in recent years have shown that nicotinic acid, in addition to a vasodilator effect, has a number of other valuable properties. Thus, in experimental atherosclerosis, nicotinic acid in large doses reduces cholesterol levels in animals and largely protects them from the development of aortic atheromatosis.</p>Kazan Medical archiveКазанский медицинский архив