Kazan medical journalKazan medical journal0368-48142587-9359Eco-Vector4704510.17816/kazmj47045MiscellaneousA.L. Lyubushin. Pathological and anatomical changes in the cerebral cortex in two cases of premature dementia (Dementia praecox). Korsakov Journal of Neuropathology and Psychiatry, No. 1 and 2, 1902KolotinskiyV.info@eco-vector.com0903190333-41491501610202016102020Copyright © 2020, Kolotinskiy V.2020<p>The study of the literature on this issue (Kahlbaum, Kiernan, Chizh, Alzheimer) leads to the conclusion that the evidence on the pathological anatomy of early dementia is extremely inadequate and unclear. The author introduces the history of illness to two patients who suffered from early dementia. Both cases ended in death; at autopsy with microscopic examination, they appeared on the face: in one case, the brain was full-blooded, slightly swollen, atrophy of the gyrus of the brain and atrophy of the cortical layer, expressed equally in all lobes of the brain. The lateral ventricles are slightly distended and contain a significant amount of fluid; in another - leptomeningitis sclerotica, Atrophia</p>Kazan Medical archiveКазанский медицинский архив