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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Kazan medical journal</journal-id><journal-title-group><journal-title xml:lang="en">Kazan medical journal</journal-title><trans-title-group xml:lang="ru"><trans-title>Казанский медицинский журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0368-4814</issn><issn publication-format="electronic">2587-9359</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">33428</article-id><article-id pub-id-type="doi">10.17816/KMJ2020-574</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Clinical observations</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Клинические наблюдения</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">A clinical case of central cancer of the lung and infiltrative tuberculosis</article-title><trans-title-group xml:lang="ru"><trans-title>Клинический случай центрального рака лёгкого и инфильтративного туберкулёза</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Naumov</surname><given-names>A G</given-names></name><name xml:lang="ru"><surname>Наумов</surname><given-names>Алексей Георгиевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>naumovag@pimunn.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Pavlunin</surname><given-names>A V</given-names></name><name xml:lang="ru"><surname>Павлунин</surname><given-names>Александр Васильевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>naumovag@pimunn.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Golova</surname><given-names>A Yu</given-names></name><name xml:lang="ru"><surname>Голова</surname><given-names>Анастасия Юрьевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>naumovag@pimunn.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Nikolskaya</surname><given-names>N A</given-names></name><name xml:lang="ru"><surname>Никольская</surname><given-names>Надежда Алексеевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>naumovag@pimunn.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Mansurskaya</surname><given-names>K V</given-names></name><name xml:lang="ru"><surname>Мансурская</surname><given-names>Ксения Валерьевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>naumovag@pimunn.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Samarina</surname><given-names>O E</given-names></name><name xml:lang="ru"><surname>Самарина</surname><given-names>Ольга Евгеньевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>naumovag@pimunn.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Privolzhsky Research Medical University</institution></aff><aff><institution xml:lang="ru">Приволжский исследовательский медицинский университет</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2020-08-12" publication-format="electronic"><day>12</day><month>08</month><year>2020</year></pub-date><volume>101</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>574</fpage><lpage>578</lpage><history><date date-type="received" iso-8601-date="2020-04-13"><day>13</day><month>04</month><year>2020</year></date><date date-type="accepted" iso-8601-date="2020-06-18"><day>18</day><month>06</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2020, Naumov A.G., Pavlunin A.V., Golova A.Y., Nikolskaya N.A., Mansurskaya K.V., Samarina O.E.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2020, Наумов А.Г., Павлунин А.В., Голова А.Ю., Никольская Н.А., Мансурская К.В., Самарина О.Е.</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="en">Naumov A.G., Pavlunin A.V., Golova A.Y., Nikolskaya N.A., Mansurskaya K.V., Samarina O.E.</copyright-holder><copyright-holder xml:lang="ru">Наумов А.Г., Павлунин А.В., Голова А.Ю., Никольская Н.А., Мансурская К.В., Самарина О.Е.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2021-01-01"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://kazanmedjournal.ru/kazanmedj/article/view/33428">https://kazanmedjournal.ru/kazanmedj/article/view/33428</self-uri><abstract xml:lang="en"><p>The scientific challenge of combining the tuberculosis process and lung cancer has not been fully disclosed in mo­dern literature. This primarily involves the low incidence of these two pathologies at the same time. This may contribute to difficulties in the qualitative and timely diagnosis of these diseases. Tuberculosis “hides” the radiological manifestations of a malignant tumor for a long time that contributing to its progression and the development of high mortality among patients. Lung cancer facilitates hemato- and lymphogenous spread of a specific pathogen. As an example, a clinical case of simultaneous occurrence of pulmonary tuberculosis and lung cancer which was observed in the patient admitted to the Department for patients with respiratory tuberculosis of Nizhny Novgorod regional clinical tuberculosis dispensary, was presented. We concluded that compliance with the algorithm of the mandatory diagnostic minimum when patients admitted to the general healthcare network, as well as compliance with the rules for population screening, especially among people over 45, will minimize the risks of delayed diagnosis in case of coexistence of respiratory tuberculosis and lung cancer.</p></abstract><trans-abstract xml:lang="ru"><p>Научная проблема, посвящённая вопросу сочетания туберкулёзного процесса и рака лёгких, в современной литературе раскрыта не полностью. В первую очередь это связано с низкой частотой этих двух видов патологии одновременно. Данное обстоятельство может способствовать возникновению сложностей в качественной и своевременной диагностике этих заболеваний. Туберкулёз длительное время «скрывает» рентгенологические проявления злокачественной опухоли, способствуя её прогрессированию и развитию высокой летальности среди больных. Рак лёгкого облегчает гемато- и лимфогенную диссеминацию специфического возбудителя. В качестве примера представлен клинический случай симультанного развития туберкулёза и рака лёгкого, который наблюдался в Нижегородском областном клиническом противотуберкулёзном диспансере в отделении для больных туберкулёзом органов дыхания. Нами сделаны выводы о том, что соблюдение алгоритма обязательного диагностического минимума при обращении пациентов с жалобами в общую лечебную сеть, а также правил диспансеризации населения, особенно среди людей старше 45 лет, позволит минимизировать риск несвоевременного выявления туберкулёза органов дыхания в сочетании с запущенным онкологическим процессом.</p></trans-abstract><kwd-group xml:lang="en"><kwd>tuberculosis</kwd><kwd>lung cancer</kwd><kwd>combination</kwd><kwd>diagnosis</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>туберкулёз</kwd><kwd>рак лёгкого</kwd><kwd>сочетание</kwd><kwd>диагностика</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Global tuberculosis report 2019. Geneva: World Health Organization. 2019; 283 p.</mixed-citation></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">Ergeshov A.E. 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