Kazan medical journalKazan medical journal0368-48142587-9359Eco-Vector228910.17816/KMJ2289Research ArticleUrogenital manifestation of climacteric syndrome, its treatmentNeymarkA I-RazdorskayaM Vx1e1n2@yandex.ruShelkovnikovaN V-Altay State Medical University, Barnaul, RussiaDepartmental Clinical Hospital, station Barnaul, Russia1504201293220821128032016Copyright © 2012, Neymark A.I., Razdorskaya M.V., Shelkovnikova N.V.2012Aim. To study of the effectiveness of the drug mesodiethylethylendibenzosulfonate (Sagenit) in women with urination disorders in the climacteric period. Methods. During the years 2009-2010 at the Department of Urology and Nephrology of Altai State Medical University were examined, treated and followed-up 40 women of the climacteric period (aged 43 to 64 years) with urination disorders. All patients were prescribed Sagenit, 1 tablet a day for 1-6 months. Results. Sagenit was well tolerated by female patients for a long period of time, had no significant side effects, which would require discontinuation of the drug. After the conducted treatment the time of urination lengthened, the volume of urination increased and the maximal urinary flow rate decreased. The positive effect of therapy (improvement of the quality of life) was reported by 75% of the surveyed women. Conclusion. Sagenit was shown to be effective in treating women with urination disorders in climacteric period.climacteric periodurogenital disordersSagenitклимактерический синдромурогенитальные расстройствасагенит[Аляев Ю.Г., Балан В.Е., Винаров А.З. и др. Медикаментозная комбинированная терапия стрессового недержания мочи у женщин в климактерическом периоде // Гинекология. - 2001. - Т. 3, №3. - С. 102-106.][Балан В.Е., Тихомирова Е.В., Ермакова Е.И. и др. Урогенитальные расстройства в климактерии. Императивные расстройства мочеиспускания в климактерии // Consil. Med. - 2004. - Т. 6, №9. - С. 34.][Балан В.Е. Альтернативный метод лечения императивных нарушений мочеиспускания у женщин // Consil. Med. - 2006. - Т. 8, №6. - С. 75-77.][Кулаков В.И., Прилепская В.Н., Назарова Н.М. Лечение урогенитальных нарушений у женщин в постменопаузе // Акуш. и гинекол. - 1997. - №5. - С. 10-12.][Тихомирова Е.В. Нарушения мочеиспускания в перименопаузе и заместительная гормонотерапия // Климактерий. - 2004. - №2. - С. 10-11.][Samsioe G. Urogenital ageing // Menopause Review. - 1998. - Vol. 3. - P. 9-17.][Ulmsten U. On urogenital ageing // Maturitas. - 1995. - Vol. 21. - P. 163-169.]