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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Kazan medical journal</journal-id><journal-title-group><journal-title xml:lang="en">Kazan medical journal</journal-title><trans-title-group xml:lang="ru"><trans-title>Казанский медицинский журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0368-4814</issn><issn publication-format="electronic">2587-9359</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">20395</article-id><article-id pub-id-type="doi">10.17816/KMJ2020-119</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Clinical experiences</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Обмен клиническим опытом</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Oncoplastic resection with trasferred perforator flaps for breast cancer patients with small/­moderate volume breasts</article-title><trans-title-group xml:lang="ru"><trans-title>Онкопластические резекции с использованием перемещённых перфорантных лоскутов у пациенток с раком молочной железы и малым/средним объёмом молочных желёз</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shatova</surname><given-names>Yu S</given-names></name><name xml:lang="ru"><surname>Шатова</surname><given-names>Юлиана Сергеевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>shat5@rambler.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Vashchenko</surname><given-names>L N</given-names></name><name xml:lang="ru"><surname>Ващенко</surname><given-names>Лариса Николаевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>shat5@rambler.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Maksimova</surname><given-names>N A</given-names></name><name xml:lang="ru"><surname>Максимова</surname><given-names>Наталья Александровна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>shat5@rambler.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Chernikova</surname><given-names>E N</given-names></name><name xml:lang="ru"><surname>Черникова</surname><given-names>Елена Николаевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>shat5@rambler.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ratieva</surname><given-names>A S</given-names></name><name xml:lang="ru"><surname>Ратиева</surname><given-names>Анастасия Сергеевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>shat5@rambler.ru</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Rostov Research Institute of Oncology</institution></aff><aff><institution xml:lang="ru">Ростовский научно-исследовательский онкологический институт</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Rostov Research Institute of Oncology</institution></aff><aff><institution xml:lang="ru">Ростовский научно-исследовательский онкологический институт г.</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2020-02-11" publication-format="electronic"><day>11</day><month>02</month><year>2020</year></pub-date><volume>101</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>119</fpage><lpage>123</lpage><history><date date-type="received" iso-8601-date="2020-02-10"><day>10</day><month>02</month><year>2020</year></date><date date-type="accepted" iso-8601-date="2020-02-10"><day>10</day><month>02</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2020, Shatova Y.S., Vashchenko L.N., Maksimova N.A., Chernikova E.N., Ratieva A.S.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2020, Шатова Ю.С., Ващенко Л.Н., Максимова Н.А., Черникова Е.Н., Ратиева А.С.</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="en">Shatova Y.S., Vashchenko L.N., Maksimova N.A., Chernikova E.N., Ratieva A.S.</copyright-holder><copyright-holder xml:lang="ru">Шатова Ю.С., Ващенко Л.Н., Максимова Н.А., Черникова Е.Н., Ратиева А.С.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://kazanmedjournal.ru/kazanmedj/article/view/20395">https://kazanmedjournal.ru/kazanmedj/article/view/20395</self-uri><abstract xml:lang="en"><p><bold>Aim.</bold> To analyze the results of oncoplastic resection with local perforator flaps for breast cancer patients with small/moderate volume breasts.</p> <p><bold>Methods.</bold> The study uncluded 31 patients undergoing oncoplastic resection with LICAP/LTAP and AIAP/MICAP flaps. Inclusion criteria: histologically confirmed breast cancer, cT1c–2N0–1M0 stage, small/moderate volume breasts, perforator presence according to Doppler ultrasound, color and energy ultrasound with linear array probe (4–18 MHz), and the patient’s desire to have the breast-conserving surgery. Exclusion criteria: large volume of breast, cT ≥3, cN ≥2, M1.</p> <p><bold>Results.</bold> LICAP-flaps were used in 19 (61.3%) cases, AIAP in 7 (22.6%) cases and LTAP-flap in 5 (16.1%) cases. Average flap width was 8.9±1.2 cm, average length 21.1±2.1 cm. In all cases the surgical margins were clear. Mean follow-up was 17.4 months. Complications occurred in 1 (3.2%) patient (hematoma with positive dynamics on conservative treatment). The necessary symmetry was achieved in 1 step in all cases. 30 (96.8%) patients were completely satisfied with the aesthetic results (excellent and good).</p> <p><bold>Conclusion.</bold> Oncoplastic resection with transferred perforator flaps can be successfully used for breast cancer patients with small/moderate volume breasts; the method does not require symmetrisation surgery, has minimum of complications and allows achieving good esthetic result.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Цель.</bold> Проанализировать результаты применения онкопластических резекций с использованием локальных перфорантных лоскутов у пациенток с раком молочной железы и малым/средним объёмом молочных желёз.</p> <p><bold>Методы.</bold> В исследование вошла 31 больная, подвергшаяся онкопластической резекции с использованием лоскутов LICAP/LTAP и AIAP/MICAP. Критерии включения: гистологически верифицированный рак молочной железы, cT1c–2N0–1M0, малый/средний объём молочных желёз, выявление перфорантов при ультразвуковом исследовании с допплерографией линейным датчиком (4–18 МГц) в режимах цветовой и энергетической допплерографии, желание больной выполнить органосохраняющую операцию. Критерии исключения: большой объём молочных желёз, cT ≥3, cN ≥2, M1.</p> <p><bold>Результаты.</bold> У 19 больных использовали лоскут LICAP (61,3%), у 7 — AIAP (22,6%), в 5 случаях — LTAP (16,1%). Средняя ширина лоскута составила 8,9±1,2 см, средняя длина — 21,1±2,1 см. Во всех случаях достигнуты чистые края резекции. Средний срок наблюдения 17,4 мес. Частота осложнений составила 3,2% — 1 больная (гематома с положительной динамикой на фоне консервативной терапии). У всех пациенток необходимая симметрия была достигнута в результате одной операции. Полностью удовлетворены полученным эстетическим результатом (отличный и хороший) 30 (96,8%) больных.</p> <p><bold>Вывод.</bold> Онкопластические резекции с использованием перемещённых перфорантных лоскутов можно успешно применять у больных раком молочной железы с малым/средним объёмом молочных желёз; методика не требует выполнения симметризирующих операций, имеет минимум осложнений и позволяет достичь хорошего эстетического результата.</p></trans-abstract><kwd-group xml:lang="en"><kwd>breast cancer</kwd><kwd>oncoplastic resection</kwd><kwd>transferred perforates flaps</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>рак молочной железы</kwd><kwd>онкопластические резекции</kwd><kwd>перемещённые перфорантные лоскуты</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Clough K.B., Kaufman G.J., Nos C. et al. Impro­ving breast cancer surgery: A classification and quadrant per quadrant atlas for oncoplastic surgery. Ann. Surg. Oncol. 2010; 17: 1375–1391. DOI: 10.1245/s10434-009-0792-y.</mixed-citation></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">Zikirya­khodzhaev A.D., Saribekyan E.K., Rasskazova E.A. Thoracoepigastric flap for breast reconstruction in cancer. Opukholi zhenskoy reproductivnoy sistemy. 2015; 11 (4): 35–38. (In Russ.) DOI: 10.17650/1994-4098-2015-11-4-35-38.</mixed-citation><mixed-citation xml:lang="ru">Зикиряходжаев А.Д., Сарибекян Э.К., Рассказова Е.А. Торакоэпигастральный лоскут для реконструкции молочной железы при раке. Опухоли женской репродуктивной системы. 2015; 11 (4): 35–38. DOI: 10.17650/1994-4098-2015-11-4-35-38.</mixed-citation></citation-alternatives></ref><ref id="B3"><label>3.</label><mixed-citation>Macmillan R.D., McCulley S.J. Breast Surgery: A companion to specialist surgical practice. Elsevier. 2019; 105–121.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Munhoz A.M., Montag E., Arruda E. et al. Assessment of immediate conservative breast surgery reconstruction: a classification system of defects revisited and an algorithm for selecting the appropriate technique. Plastic and Reconstructive Surg. 2008; 121 (3): 716–727. DOI: 10.1097/01.prs.0000299295.74100.fa.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Clough K., Kroll S., Audretsch W. An approach to the repair of partial mastectomy defects. Plastic and Reconstructive Surg. 1999; 104 (2): 409–420. DOI: 10.1097/00006534-199908000-00014.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Munhoz A.M., Montag E., Arruda E. et al. Immediate conservative breast surgery reconstruction with perforator flaps: New challenges in the era of partial mastectomy reconstruction? The Breast. 2011; 20 (3): 233–240. DOI: 10.1016/j.breast.2011.01.001.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Zhygulin A., Palytsia V., Vinnytska D., Nedielchev V. “Invisible surgery” — concept of oncoplastic breast conserving surgery for selected patients. Eur. J. Surg. Oncol. 2019; 45 (2): e38. DOI: 10.1016/j.ejso.2018.10.162.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Hamdi M. Oncoplastic and reconstructive surgery of the breast. The Breast. 2013; 22 (S2): S100–S105. DOI: 10.1016/j.breast.2013.07.019.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Hamdi M., Van Landuyt K., de Frene B. et al. The versatility of the inter-costal artery perforator (ICAP) flaps. J. Plastic, Reconstructive &amp; Aesthetic Surg. 2006; 59 (6): 644–652. DOI: 10.1016/j.bjps.2006.01.006.</mixed-citation></ref><ref id="B10"><label>10.</label><citation-alternatives><mixed-citation xml:lang="en">Maksimova N.A., Przhedetsky Yu.V., Khokhlova O.V. et al. Ultrasoundscanin planning surgery for cutaneous melanoma of theextremities. Sibirskiy onkolo­gicheskiy zhurnal. 2019; 18 (1): 95–102. (In Russ.) DOI: 10.21294/1814-4861-2019-18-1-95-102.</mixed-citation><mixed-citation xml:lang="ru">Максимова Н.А., Пржедецкий Ю.В., Хохлова О.В. и др. Ультразвуковое исследование при планировании операций по поводу меланомы кожи конечностей. Сибирский онкол. ж. 2019; 18 (1): 95–102. DOI: 10.21294/1814-4861-2019-18-1-95-102.</mixed-citation></citation-alternatives></ref><ref id="B11"><label>11.</label><mixed-citation>Hamdi M., Van Thielen J. Pedicled and free flaps in oncoplastic surgery. In: Plastic Surgery. Volume 5: Breast.Elsevier. 2017; 442–457.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Hamdi M., Van Landuyt K., Monstrey S., Blon­deel P. Pedicled perforator flaps in breast reconstruction: a new concept. Brit. J. Plastic Surg. 2004; 57 (6): 531–539. DOI: 10.1016/j.bjps.2004.04.015.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Macmillan R.D., Carstensen L., Tan V. et al. Local perforator flaps in oncoplastic breast conserving surgery: Nottingham's experience. In: Losken A., Hamdi M. (eds). Partial breast reconstruction: techniques in oncoplastic surgery. Quality Medical Publishing. 2017; 672 р.</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Hamdi M., Spano A., Landuyt K. et al. The late­ral intercostal artery perforators: Anatomical study and clinical application in breast surgery. Plastic and Reconstructive Surg. 2008; 121 (2): 389–396. DOI: 10.1097/01.prs.0000298317.65296.cf.</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Bhattacharya S., Bhagia S.P., Bhatnagar S.K. et al. The anatomical basis of the lateral thoracic flap. Eur. J. Plastic Surg. 1990; 13 (6): 238–240. DOI: 10.1007/BF00208322.</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>McCulley S.J., Schaverien M.V., Tan V.K., et al. Lateral thoracic artery perforator (LTAP) flap in partial breast reconstruction. J. Plastic Reconstructive and Aesthetic Surg. 2015; 68 (5): 686–691. DOI: 10.1016/j.bjps.2015.01.008.</mixed-citation></ref></ref-list></back></article>
