Kazan medical journalKazan medical journal0368-48142587-9359Eco-Vector1944510.17816/KMJ2020-84Research ArticleMortality of the population of the Omsk region as a result of acute poisoning and exposure to toxic substances in 2009–2018SabaevA Valesabaev@yandex.ruGolevaO Palesabaev@yandex.ruOmsk State Medical University11022020101184900802202008022020Copyright © 2020, Sabaev A.V., Goleva O.P.2020<p><strong>Aim.</strong> To study the dynamics of mortality rates in the Omsk region as a result of acute poisoning and toxic effects for 20092018.</p>
<p><strong>Methods.</strong> In the statistical processing of research materials, alternative (intensive indicators) analysis and graphical analysis methods were used, time-series parameters were calculated, time series was modelled on the basis of the approximating function using a polynomial of the 2nd degree.</p>
<p><strong>Results.</strong> In the Omsk region the mortality rate recorded due to acute poisoning and exposure to toxic substances decreased by 2.0 times during the survey period, including decrease in the urban population by 2.3 times and among rural residents by 1.5 times. The mortality rate of the population due to the toxic effects of alcohol and its surrogates was decreased by 2.0 times, due to narcotic substances 6.5 times, due to corrosive poisons 2.0 times, due to toxic gases 2.1 times, due to non-classified poisons 3.0 times. The dynamics of mortality as a result of drug poisoning and poisoning by industrial poisons in the region was unstable, decrease in the level of indicators by the end of the analyzed period is statistically insignificant. Since 2015, fatal cases of toxic effects of psychodysleptics based on modern modified substances with narcotic effects were recorded in the region; by the end of the study period, mortality increased by 77.0% due to this pathology, which has a statistically significant confirmation.</p>
<p><strong>Conclusion.</strong> With an obvious improvement in the medical and demographic indicators due to poisoning and toxic effects in the region, there are changes associated with the emergence and spread of new chemicals with narcotic effects that affect the formation of the toxicological situation in the region.</p>mortalityacute poisoningtoxic effectsсмертностьострые отравлениятоксические воздействия[Medicinskaya toksikologiya. Nacional'noe rukovodstvo. (Medical toxicology. National guidance.) Ed. E.A. Luzhnikov. Moscow: GEOTAR-media. 2012; 928 p. (In Russ.)][Ostapenko Yu.N., Kovalyov A.V., Gasimova Z.M., Zajkovskij V.V. Toxicological aid to population of the Russian Federation: status and problems. Toxicological Bulletin. 2014; (3): 2–8. (In Russ.)][Goleva O.P., Sabaev A.V. The dynamics of the indicators of population mortality in Omskaya oblast as a result of acute chemical intoxications in 2001–2010. Prob. soc. hygiene, health and medical history. 2011; (4): 10–13. (In Russ.)][Narkologiya. Nacional'noe rukovodstvo. (Narcology. National manual.) Ed. by N.N. Iwaniec, I.P. Anokhina, V.A. Vinnikova. 2nd ed., pererab. and additional. M.: GEOTAR-Media. 2016; 944 p. (In Russ.)][Sabaev A.V., Goleva O.P. The dynamics of population mortality due to acute alcoholic intoxications in the Russian Federation. Prob. soc. hygiene, health and medical history. 2012; (4): 21–23. (In Russ.)][Sabaev A.V. Acute alcohol-related mortality of the Omsk region population for 2002–2011. Russian medical news. 2014; 19 (2): 46–48. (In Russ.)][Sabaev A.V., Goleva O.P. Mortality in the Omsk region as a result of narcotic substances poisonings (2002–2011). Narcology. 2013; (2): 35–37. (In Russ.)][Ostapenko Yu.N., Belova M.V., Klyuev A.E. et al. Acute poisoning with psychoactive cannabimimetic substances. clinical picture, diagnostics, treatment. Medline.ru. 2015; 16 (1): 176–186. (In Russ.)][Zobnin Yu.V., Stadler E.M. Acute poisoning with synthetic cannabinoids (“spice”). Siberian medical journal (Irkutsk). 2014; (8): 130–135. (In Russ.)]