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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Kazan medical journal</journal-id><journal-title-group><journal-title xml:lang="en">Kazan medical journal</journal-title><trans-title-group xml:lang="ru"><trans-title>Казанский медицинский журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0368-4814</issn><issn publication-format="electronic">2587-9359</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1641</article-id><article-id pub-id-type="doi">10.17750/KMJ2015-1061</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Assistance to the practicing physician</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>В помощь практическому врачу</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Neurological and psychological status in acute stage of ischemic stroke</article-title><trans-title-group xml:lang="ru"><trans-title>Динамика нейропсихологического статуса пациентов в остром периоде ишемического инсульта</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Dementeva</surname><given-names>O V</given-names></name><name xml:lang="ru"><surname>Дементьева</surname><given-names>Олеся Владимировна</given-names></name></name-alternatives><email>ovdementeva@bk.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Starikova</surname><given-names>N L</given-names></name><name xml:lang="ru"><surname>Старикова</surname><given-names>Наталья Леонидовна</given-names></name></name-alternatives><email>ovdementeva@bk.ru</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Municipal Clinical Hospital №4, Perm, Russia</institution></aff><aff><institution xml:lang="ru">Городская клиническая больница №4</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Perm State Medical University named after Academician E.A. Wagner, Perm, Russia</institution></aff><aff><institution xml:lang="ru">Пермский государственный медицинский университет им. Е.А. Вагнера</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2015-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2015</year></pub-date><volume>96</volume><issue>6</issue><issue-title xml:lang="en">VOL 96, NO6 (2015)</issue-title><issue-title xml:lang="ru">ТОМ 96, №6 (2015)</issue-title><fpage>1061</fpage><lpage>1065</lpage><history><date date-type="received" iso-8601-date="2016-03-28"><day>28</day><month>03</month><year>2016</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2015, Dementeva O.V., Starikova N.L.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2015, Дементьева О.В., Старикова Н.Л.</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="en">Dementeva O.V., Starikova N.L.</copyright-holder><copyright-holder xml:lang="ru">Дементьева О.В., Старикова Н.Л.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://kazanmedjournal.ru/kazanmedj/article/view/1641">https://kazanmedjournal.ru/kazanmedj/article/view/1641</self-uri><abstract xml:lang="en"><p><bold>Aim.</bold> Assess the changes of neurological and psychological status in patients with acute stage of the first ischemic stroke.</p> <p><bold>Methods.</bold> The study included 25 patients with ischemic stroke, the average age was 65.72±12.49 years. Neuropsychological examination was performed using a Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment scale (MoCA), Beck Depression Inventory, Spielberger State-Trait Anxiety Inventory, Lazarus Ways of Coping Questionnaire. All studies were performed twice on day 1-3 and on day 19-21 after the stroke.</p> <p><bold>Results.</bold> Mild motor dysfunction by National Institute of Health Stroke Scale (NIHHS) was registered at admission. By the end of the acute period, positive changes were registered: NIHSS score decreased by 66.4%, significant improvement in patient’s cognitive status was seen. The average depression score by Beck Depression Inventory was 15.6 points, with severe depression diagnosed in 2 patients. By the end of the acute period, depressive symptoms regressed to the average level of 11.1 points. Reactive anxiety at admission was low, personal anxiety - high. By the end of the acute period anxiety remained at the same level or slightly reduced. Direct correlations of the neurological deficit degree by NIHSS and depression score by Beck Depression Inventory, as well as the later with personal anxiety level were revealed. Inverse correlation between the MMSE cognitive status and depression levels was discovered.</p> <p><bold>Conclusion.</bold> By the end of the acute period, the severity of emotional disorders decreases and cognitive function improves together with restoring motor activity.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Цель.</bold> Оценить динамику нейропсихологического статуса пациентов на протяжении острого периода первого ишемического инсульта.</p> <p><bold>Методы.</bold> Обследованы 25 пациентов с ишемическим инсультом, средний возраст составил 65,72±12,49 года. Проводили нейропсихологическое обследование с применением краткой шкалы оценки психического статуса (MMSE), монреальской шкалы оценки когнитивных функций (MoCA), шкалы депрессии Бека, шкалы тревожности Спилбергера, опросника копинг-стратегий Лазаруса. Все исследования проводили дважды: на 1-3-й день развития инсульта и на 19-21-й день.</p> <p><bold>Результаты.</bold> При поступлении наблюдалась лёгкая степень двигательных нарушений по шкале тяжести инсульта Национального института здоровья CША (National Institute of Health Stroke Scale - NIHHS). К концу острого периода развивалась положительная динамика, показатель по шкале NIHSS уменьшился на 66,4%, также была отмечена значительная положительная динамика в отношении когнитивного статуса пациентов. Уровень депрессии в начале заболевания по опроснику Бека составлял в среднем 15,6 балла, у 2 пациентов выявлена депрессия тяжёлой степени. К концу острого периода симптомы депрессии регрессировали, в среднем уровень депрессии составил 11,1 балла. Реактивная тревожность при поступлении была низкой, личностная - высокой. Тревожность пациентов к концу острого периода либо осталась на прежнем уровне, либо незначительно снизилась. Обнаружены прямые корреляции степени неврологического дефицита по NIHSS и уровня депрессии по шкале Бека, уровня депрессии и уровня личностной тревожности. Выявлена обратная корреляция показателя когнитивного статуса по MMSE и уровня депрессии.</p> <p><bold>Вывод.</bold> К концу острого периода на фоне улучшения двигательной активности уменьшается уровень эмоциональных нарушений и улучшаются когнитивные функции пациентов.</p></trans-abstract><kwd-group xml:lang="en"><kwd>stroke</kwd><kwd>depression</kwd><kwd>anxiety</kwd><kwd>ways of coping</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>инсульт</kwd><kwd>депрессия</kwd><kwd>тревога</kwd><kwd>копинг-стратегии</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Гусев Е.И., Коновалов А.Н., Скворцова В.И., Гехт А.Б. Неврология. Национальное руководство. М.: ГЭОТАР-Медиа. 2009; 1040 с.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Гусев Е.И., Скворцова В.И., Стаховская Л.В. Эпидемиология инсульта в России. 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