Kazan medical journalKazan medical journal0368-48142587-9359Eco-Vector1334910.17816/10.17816/KMJ2019-492Research ArticleSome difficulties of differential diagnosis of clonorchiasisFigurnovV Acanceromatoz1989@gmail.comDolgikhT Acanceromatoz1989@gmail.comGrigorenkoA Acanceromatoz1989@gmail.comDubyagaE Vcanceromatoz1989@gmail.comRoshchinS Ncanceromatoz1989@gmail.comNitsievskayaL Scanceromatoz1989@gmail.comTrynovN Ncanceromatoz1989@gmail.comAmur State Medical AcademyAmur Regional Oncology CenterAmur Regional Clinical HospitalAmur Regional Infectious Diseases Hospital1306201910034924941006201910062019Copyright © 2019, Figurnov V.A., Dolgikh T.A., Grigorenko A.A., Dubyaga E.V., Roshchin S.N., Nitsievskaya L.S., Trynov N.N.2019<p>Clonorchiasis is a disease caused by the parasites of the Chinese fluke (Clonorchis sinensis) characterized by damage of the liver and/or pancreas. The basis of the diagnosis of clonorchiasis is detection of parasite eggs in the feces. Despite this, it may be difficult to confirm this helminthiasis. It should be noted that in case of low-intensity invasions or in the acute period of clonorchiasis, it is not always possible to detect eggs in the feces. The article describes a case of a 38-year-old man admitted to the hospital with a preliminary diagnosis of liver tumor. The diagnosis of clonorchiasis was made after the liver biopsy and identifying of Clonorchis eggs in the duodenal contents. No eggs were found in the feces. The therapy with praziquantel (biltricide) was effective and the patient was discharged in a satisfactory condition.</p>clonorchiasisliverклонорхозпечень[Chelomina G.N. Clonorchiasis: global and regional epidemiology. Meditsinskaya parazitologiya. 2017; (2): 55–61. (In Russ.)][Baykova O.A., Nikolaeva N.N., Grishchenko E.G. et al. Liver trematode infection — opisthorchiasis and clonorchiasis: actual problems and principles of diagnosis in modern clinical practice (review of literature). Bulleten’ VSNTs SO RAMN. 2016; 1 (6): 182–187. (In Russ.)]