Kazan medical journalKazan medical journal0368-48142587-9359Eco-Vector1049910.17816/KMJ2018-876Research ArticlePulmonary hypertension and respiratory function in parenchyma sparing surgical treatment of lung cancerKirshinA Akirshinalex80@mail.ruNapol'skikhV Mkirshinalex80@mail.ruRepublican Clinical Oncological Dispensary n.a. S.G. PrimushkoIzhevsk State Medical Academy, department of oncology2511201899687687926112018Copyright © 2018, Kirshin A.A., Napol'skikh V.M.2018<p><strong>Aim.</strong> To assess the effect of pulmonary hypertension on respiratory function in lung cancer surgery.</p>
<p><strong>Methods.</strong> 92 patients diagnosed with non-small cell lung cancer, among them 69 men (75 %) and 23 women (25 %), were operated on with different variants of angioplastic lobectomy (APL), the average age was 57.8 6.7 years. 91 patients underwent pulmonectomy (PE), among them 87 men (95.6 %) and 4 women (4.4 %), the average age was 59 8.8 years.</p>
<p><strong>Results.</strong> One year after angioplastic lobectomy FEV1 decreased by 0.69 liters (27 %), vital capacity decreased by 1.17 liters (32.9 %), FVC (the difference between the volumes of lungs at the beginning and at the end of forced expiration) reduced by 0.64 liters (20.5 %). After removal of the lung, dynamics of the decrease of similar indicators was 1.02 (42 %); 1.53 (43.8 %); 1.24 (40.3 %) liter respectively. The presence of a negative relationship between PA/A (pulmonary artery/aorta) and FEV1 was revealed. Thus, in the group of angioplastic lobectomy without initial pulmonary hypertension (PA/A less than 1) it was found that r = -0.42 (p 0.01), with pulmonary hypertension (PA/A 1 or more) r = -0.4 (p 0.01). In the group of pulmonectomy without initial pulmonary hypertension, the correlation index was -0.38 (p 0.01), with initial pulmonary hypertension r = -0.33 (p 0.01).</p>
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