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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Kazan medical journal</journal-id><journal-title-group><journal-title xml:lang="en">Kazan medical journal</journal-title><trans-title-group xml:lang="ru"><trans-title>Казанский медицинский журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0368-4814</issn><issn publication-format="electronic">2587-9359</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">100663</article-id><article-id pub-id-type="doi">10.17816/kazmj100663</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Pharmacy</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Фармация</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Antihypoxic and analgesic activity of some species of hollywort</article-title><trans-title-group xml:lang="ru"><trans-title>Противогипоксическая и анальгезирующая активности некоторых видов остролодочника</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Bakhtina</surname><given-names>S. M.</given-names></name><name xml:lang="ru"><surname>Бахтина</surname><given-names>С. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Pharmacology, Department of Pharmacy Technology of Drugs</p></bio><bio xml:lang="ru"><p>Кафедра фармакологии, кафедра аптечной технологии лекарств</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Lesiovskaya</surname><given-names>E. E.</given-names></name><name xml:lang="ru"><surname>Лесиовская</surname><given-names>Е. Е.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Pharmacology, Department of Pharmacy Technology of Drugs</p></bio><bio xml:lang="ru"><p>Кафедра фармакологии, кафедра аптечной технологии лекарств</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Sakanyan</surname><given-names>E. I.</given-names></name><name xml:lang="ru"><surname>Саканян</surname><given-names>Е. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Pharmacology, Department of Pharmacy Technology of Drugs</p></bio><bio xml:lang="ru"><p>Кафедра фармакологии, кафедра аптечной технологии лекарств</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Konopleva</surname><given-names>E. V.</given-names></name><name xml:lang="ru"><surname>Коноплева</surname><given-names>Е. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Pharmacology, Department of Pharmacy Technology of Drugs</p></bio><bio xml:lang="ru"><p>Кафедра фармакологии, кафедра аптечной технологии лекарств</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kabishev</surname><given-names>K. E.</given-names></name><name xml:lang="ru"><surname>Кабишев</surname><given-names>К. Э.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Pharmacology, Department of Pharmacy Technology of Drugs</p></bio><bio xml:lang="ru"><p>Кафедра фармакологии, кафедра аптечной технологии лекарств</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">St. Petersburg Chemical and Pharmaceutical Institute</institution></aff><aff><institution xml:lang="ru">Санкт-Петербургский химико-фармацевтический институт</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="1995-05-15" publication-format="electronic"><day>15</day><month>05</month><year>1995</year></pub-date><volume>76</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>205</fpage><lpage>207</lpage><history><date date-type="received" iso-8601-date="2022-02-13"><day>13</day><month>02</month><year>2022</year></date><date date-type="accepted" iso-8601-date="2022-02-13"><day>13</day><month>02</month><year>2022</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 1995, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 1995, Эко-Вектор</copyright-statement><copyright-year>1995</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://kazanmedjournal.ru/kazanmedj/article/view/100663">https://kazanmedjournal.ru/kazanmedj/article/view/100663</self-uri><abstract xml:lang="en"><p>The problem of anesthesia has always occupied one of the central places in medicine. Among pain relievers, narcotic analgesics are the most important, but their use is fraught with the danger of drug dependence and is associated with numerous complications. The search for more effective and less dangerous painkillers is urgent. The most promising should be considered the development of such analgesics that have analgesic and antihypoxic effects, since hypoxia significantly aggravates the course of many pathological processes [3, 4].</p></abstract><trans-abstract xml:lang="ru"><p>Проблема обезболивания всегда занимала одно из центральных мест в медицине. Среди болеутоляющих средств наибольшее значение имеют наркотические анальгетики, но их применение таит в себе опасность лекарственной зависимости и сопряжено с многочисленными осложнениями. Актуален поиск более эффективных и менее опасных обезболивающих препаратов. Наиболее перспективной следует считать разработку таких анальгезирующих средств, которые обладают обезболивающим и противогипоксическим действиями, поскольку гипоксия существенно усугубляет течение многих патологических процессов [3, 4].</p></trans-abstract><kwd-group xml:lang="en"><kwd>Kazan Medical archive</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>Казанский медицинский архив</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Звартау Э. Э., Коваленко В. С. Нейропсихофармакология болеутоляющих средств.— Л., 1986</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Пастушенков Л. Б. Фармакологическая коррекция гипоксических состояний.— М., 1989</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Пастушенков Л. В., Лесиовская Е. Е. Растения — антигипоксанты (Фитотерапия) — СПб, 1991</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Пастушенков Л. 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