Kazan medical journalKazan medical journal0368-48142587-9359Eco-Vector10063410.17816/kazmj100634Research ArticleExperimental pharmacotherapy of toxic brain edema by nonanticholinesterasic phosphoroorganic compoundsKhafizyanovaR. H.<p>Department of Pharmacology</p>info@eco-vector.comKazan Medical University150519957631982011302202213022022Copyright © 1995, Eco-Vector1995<p>Experimental study of the effect of dimephosphone, phosphabenzide, preparations № 305 and № 155 examples of various groups of synthetic nonanticholinesterasic phosphoroorganic compounds, on the development of toxic brain edema in rats, caused by injection of nicotine and monoiodacetate, reveal their antiedematic property. The results of investigations show prospects of a search of new effective medicinal agents for prevention and treatment of brain edema among phosphoroorganic compounds which do not show anticholinesttrasic activity.</p>Kazan Medical archiveКазанский медицинский архив