Kazan medical journalKazan medical journal0368-48142587-9359Eco-Vector10062710.17816/kazmj100627Research ArticleSynthesis, properties and biological activity of bis(diphenylphosphinylacetyl)hydrazine and its complex with iron (III)TavasovaR. I.<p>Department of Organic Chemistry, Department of Pharmaceutical Chemistry, Department of Pharmacology</p>info@eco-vector.comMoskvaV. V.<p>Department of Organic Chemistry, Department of Pharmaceutical Chemistry, Department of Pharmacology</p>info@eco-vector.comVoskresenskayaO. V.<p>Department of Organic Chemistry, Department of Pharmaceutical Chemistry, Department of Pharmacology</p>info@eco-vector.comLitvinenkoA. V.<p>Department of Organic Chemistry, Department of Pharmaceutical Chemistry, Department of Pharmacology</p>info@eco-vector.comSeminaI. I.<p>Department of Organic Chemistry, Department of Pharmaceutical Chemistry, Department of Pharmacology</p>info@eco-vector.comBaichurinaA. Z.<p>Department of Organic Chemistry, Department of Pharmaceutical Chemistry, Department of Pharmacology</p>info@eco-vector.comRzhevskayaG. F.<p>Department of Organic Chemistry, Department of Pharmaceutical Chemistry, Department of Pharmacology</p>info@eco-vector.comKazan Technological UniversityKazan Medical University150519957631931961302202213022022Copyright © 1995, Eco-Vector1995<p>The synthesis of bis (diphcnulphosphinylacetyl)hydrazine and its complex with iron (III) chloride is performed, their ultraviolet and infrared spectrums are investigated, the method of titrimetric determination of iron in the complex is developed. The initial ligand offers tranquilizing, antidepressive activity and does not affect the lenth of ethanol anesthesia of rats, and its complex with iron (III) chloride potentiates the lenth of ethanol anesthesia more than 3 times, however, does not manifest tranquilizing and antidepressive activity. Both of the products are low toxic compounds.</p>azan Medical ArchivКазанский медицинский архивK