Study of the Effect of Nonselective Organic Solvent Nature on the Self-Organization of Amphiphilic Block Copolymers of D,L-Lactide and Ethylene Oxide in Aqueous Solution

E. V. Kuznetsova; Кузнецова Е. В.; E. M. Shirokova; Широкова Е. М.; Yu. A. Puchkova; Пучкова Ю. А.; E. V. Yastremsky; Ястремский Е. В.; S. N. Chvalun; Чвалун С. Н.

doi:10.31857/S2308114723700279

Study of the Effect of Nonselective Organic Solvent Nature on the Self-Organization of Amphiphilic Block Copolymers of D,L-Lactide and Ethylene Oxide in Aqueous Solution

Autores: Kuznetsova E.V.¹, Shirokova E.M.¹, Puchkova Y.A.¹, Yastremsky E.V.², Chvalun S.N.¹^,3
Afiliações:
1. National Research Center “Kurchatov Institute”
2. Federal Research Center “Crystallography and Photonics,” Russian Academy of Sciences
3. Enikolopov Institute of Synthetic Polymer Materials, Russian Academy of Sciences
Edição: Volume 65, Nº 1 (2023)
Páginas: 138-152
Seção: Articles
URL: https://kazanmedjournal.ru/2308-1147/article/view/674813
DOI: https://doi.org/10.31857/S2308114723700279
EDN: https://elibrary.ru/HSGETL
ID: 674813

Citar

Texto integral

Acesso aberto
Acesso é fechado

Acesso está concedido
Acesso é fechado

Somente assinantes

Resumo
Sobre autores
Bibliografia
Arquivos suplementares
Estatísticas

Resumo

The self-organization of biocompatible amphiphilic block copolymers of D,L-lactide and ethylene oxide with various hydrophobic poly(D,L-lactide) block length in aqueous media has been investigated. It has been shown that the nature of nonselective organic solvent has a considerable effect on the size, size polydispersity, and morphology of micelles of a block copolymer with a long poly(D,L-lactide) block. To elucidate the dependence of properties of block copolymer micelles on the common organic solvent type (acetone, tetrahydrofuran, N,N-dimethylformamide, and acetonitrile) various parameters of the used solvents have been estimated, and correlation between the Flory–Huggins coefficient and the surface tension between the hydrophobic block and the nonselective organic solvent and the parameters of micellar structures has been found.

Bibliografia

Nagarajan R., Ganesh K. // J. Chem. Phys. 1989. V. 90. P. 5843.
Mai Y., Eisenberg A. // Chem. Soc. Rev. 2012. V. 41. P. 5969; Jin B., Chen Y., Luo Y., Li X. // Chinese J. Chem. 2022. V. 41. P. 93; Choicair A., Eisenberg A. // Eur. Phys. J. E. 2003. V. 10. P. 37.
Phan H., Minut R.I., McCrorie P., Vasey C., Larder R.R., Krumins E., Marlow M., Rahman R., Alexander C., Taresco V., Pearce A.K. // J. Polym. Sci., Polym. Chem. 2019. V. 57. P. 1801.
Razuvaeva E.V., Kulebyakina A.I., Streltsov D.R., Bakirov A.V., Kamyshinsky R.A., Kuznetsov N.M., Chvalun S.N., Shtykova E.V. // Langmuir. 2018. V. 34. P. 15470.
Kadina Y.A., Razuvaeva E.V., Streltsov D.R., Sedush N.G., Shtykova E.V., Kulebyakina A.I., Puchkov A.A., Volkov D.S., Nazarov A.A., Chvalun S.N. // Molecules. 2021. V. 26. P. 602.
Desyatskova A.M., Kuznetsova E.V., Puchkova Y.A., Yastremsky E.V., Bakirov A.V., Dmitryakov P.V., Buzin A.I., Chvalun S.N. // Mendeleev Commun. 2023. V. 33. P. 86.
Sedush N.G., Kadina Y.A., Razuvaeva E.V., Puchkov A.A., Shirokova E.M., Gomzyak V.I., Kalinin K.T., Kulebyakina A.I., Chvalun S.N. // Nanobiotechnol. Rep. 2021. V. 16. P. 421.
Ali I., Kareem F., Rahim S., Perveen S., Ahmed S., Shah M.R., Malik M.I. // React. Funct. Polym. 2020. V. 150. P. 104553.
Efimova A.A., Sybachin A.V., Chvalun S.N., Kulebyakina A.I., Kozlova E.V., Yaroslavov A.A. // Polymer Science B. 2015. V. 57. № 2. P. 140.
Efimova A.A., Chvalun S.N., Kulebyakina A.I., Kozlova E.V., Yaroslavov A.A. // Polymer Science A. 2016. V. 58. № 2. P. 172.
Alexis F., Pridgen E., Molnar L.K., Farokhzad O.C. // Mol. Pharm. 2008. V. 5. P. 505.
Lin Z., Xi L., Chen S., Tao J., Wang Y., Chen X., Li P., Wang Z., Zheng Y. // Acta Pharm. Sin. B. 2021. V. 11. P. 1047.
Crucho C.I.C., Barros M.T. // Mater. Sci. Eng. C. 2017. V. 80. P. 771.
Yu Y., Zhang L., Eisenberg A. // Macromolecules. 1998. V. 31. P. 1144.
Bhargava P., Zheng J.X., Li P., Quirk R.P., Harris F.W., Cheng S.Z.D. // Macromolecules. 2006. V. 39. P. 4880.
Riley T., Stolnik S., Heald C.R., Xiong C.D., Garnett M.C., Illum L., Davis S.S., Purkiss S.C., Barlow R.J., Gellert P.R. // Langmuir. 2001. V. 17. P. 3168.
Pijpers I.A.B., Meng F., van Hest J.C.M., Abdelmohsen L.K.E.A. // Polym. Chem. 2020. V. 11. P. 275.
Simonutti R., Bertani D., Marotta R., Ferrario S., Manzone D., Mauri M., Gregori M., Orlando A., Masserini M. // Polymer. 2021. V. 218. P. 123511.
Astafieva I., Zhong X.F., Eisenberg A. // Macromolecules. 1993. V. 26. P. 7339.
Ahmed F., Discher D.E. // J. Control. Release. 2004. 96. P. 37.
Tomaszewska E., Soliwoda K., Kadziola K., Tkacz-Szczesna B., Celichowski G., Cichomski M., Szmaja W., Grobelny J. J. Nanomater. 2013. V. 2013. P. 1.
de Oliveira A.M., Jӓger E., Jӓger A., Stepánek P., Giacomeli F.C. // Colloids Surf. A. 2013. V. 436. P. 1092.
Kuznetsova E.V., Kuznetsov N.M., Kalinin K.T., Lebedev-Stepanov P.V., Novikov A.A., Chvalun S.N. // Colloid J. 2022. V. 84. P. 704.
Glova A.D., Falkovich S.G., Dmitrienko D.I., Lyulin A.V., Larin S.V., Nazarychev V.M., Karttunen M., Lyulin S.V. // Macromolecules. 2018. V. 51. P. 552.
Zheng J.X., Xiong H., Chen W.Y., Lee K., Van Horn R.M., Quirk R.P., Lotz B., Thomas E.L., Shi A.-C., Cheng S.Z.D. // Macromolecules. 2006. V. 39. P. 641.
Nagarajan R. // J. Colloid Interface Sci. 2015. V. 449. P. 416.
Baker G.L., Vogel E.B., Smith III M.R. // Polym. Rev. 2008. V. 48. P. 64.
Witschi C., Doelker E. // Eur. J. Pharmac. Biopharmac. 1997. V. 43. P. 215.
Properties of solvents used in organic chemistry. http://murov.info/orgsolvents.htm (accessed on April 20, 2023).
Subrahmanyam R., Gurikov P., Dieringer P., Sun M., Smirnova I. // Gels. 2015. V. 1. P. 291.
Ovejero G., Pérez P., Romero M.D., Guzmán I., Diʹez E. // Eur. Polym. J. 2007. V. 43. P. 1444.
Glova A.D., Melnikova S.D., Mercurieva A.A., Larin S.V., Lyulin S.V. // Polymers. 2019. V. 11. P. 2056.
Garfield L.J., Petrie S.E. // J. Phys. Chem. 1964. V. 68. P. 1750.
Chow T.S. // Macromolecules. 1980. V. 13. P. 362.
Hansen solubility parameters. A user’s handbook. Second ed. /Ed. by C.M. Hansen. Boca Raton: CRC Press Taylor & Francis, 2007.
Venkatram S., Kim C., Chandrasekaran A., Ramprasad R. // J. Chem. Inf. Model. 2019. V. 59. P. 4188.