TOXICOLOGICAL HAZARD ASSESSMENT OF A NEW COMPLEX ORGANOMINERAL MICROFERTILIZER

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The article is devoted to the study of the nature of the toxic effects of a new complex organic mineral fertilizer on the organism of laboratory animals. The assessment of its toxicity and hazard has been performed with the definition of acute and subacute toxicity parameters, as well as irritant effect on skin and mucous membranes, sensitizing and cumulative effects.

About the authors

A. V. Istomin

F.F. Erisman Federal Research Center of Hygiene of Rospotrebnadzor

Author for correspondence.
Email: fncg@yandex.ru

Istomin Aleksandr Viktorovich

141014, Mytishchi, Moscow Region

Russian Federation

L. A. Rumyantseva

F.F. Erisman Federal Research Center of Hygiene of Rospotrebnadzor

Email: pesticidi@fferisman.ru

Rumyantseva Larisa Aleksandrovna

141014, Mytishchi, Moscow Region

Russian Federation

O. V. Vetrova

F.F. Erisman Federal Research Center of Hygiene of Rospotrebnadzor

Email: fncg@yandex.ru

Vetrova Olga Viktorovna

141014, Mytishchi, Moscow Region

Russian Federation

I. G. Mikhailov

F.F. Erisman Federal Research Center of Hygiene of Rospotrebnadzor

Email: pesticidi@fferisman.ru

Mikhailov Ivan Georgievich

141014, Mytishchi, Moscow Region

Russian Federation

References

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  2. Vetrova O.V., Istomin A.V. Relevance of issues of hygienic safety in the production of mineral fertilizers at the regional level / Materials of the international Congress “Nutrition and health”. – Moscow. – 2013. – P. 20 (in Russian).
  3. Harmful substances in the environment. Elements of groups 1-IV of the periodic table and their inorganic compounds. Ref.- Enc. ed. /ed. V.A. Filov et.al. – SPb.: NPO “Professional”, 2012. -464 p (in Russian).
  4. SanPiN 1.2.2584-10 “Hygienic requirements for the safety of testing, storage, transportation, sale, use, neutralization and disposal of pesticides and agrochemicals” (Annex 1) (in Russian).
  5. Loyt A.O. Preventive toxicology. Primary toxicological assessment of chemical substances. – St. Petersburg: Teza, 1996. – 36 p. (in Russian).
  6. Novikov S.M., Fursova T.N. Method of quantitative assessment of cumulative properties of harmful substances / Hygiene and sanitation. – 1987. – No. 10. – Pp. 52-55 (in Russian).
  7. MU 1.2.1105-02 “Assessment of the toxicity and hazard of disinfectants”. – M. 2002 (in Russian).
  8. Assessment of the toxicity and hazard of chemicals and their mixtures for human health: Guidance. – Moscow: Federal Center for Hygiene and Epidemiology of Rospotrebnadzor, 2014. – 639 p. (in Russian).
  9. Potapov A.I., Rakitskiy V.N., Bereznyak I.V. Complex impact of chemical substances in the conditions of industrial and agricultural production /ed. by A.I. Potapov et al. – Moscow: Shiko, 2012. – 176 p. (in Russian).
  10. Tulakin A.V., Mekhant’eva L.E. Hygiene of the environment and production environment of mineral fertilizers enterprises / ed. by A. I. Potapov. – M, 2007. – 220 p. (in Russian).

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Copyright (c) 2020 Istomin A.V., Rumyantseva L.A., Vetrova O.V., Mikhailov I.G.


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